Report by the EBC Analysis Committee on the Determination of NDMA in Beer by GC-TEA or GC-MS Detection (2009 Collaborative Trial)

Approved by the Analysis Committee for inclusion in the EBC Analytica

Abstract

The determination of NDMA in beer by the method of GC-TEA or GC-MS was collaboratively tested by the EBC Analysis Committee according to ISO standard 5725-2: 1994. Repeatability (r95) and reproducibility (R95) values are presented. There is statistically significant evidence (Spearman rho = 0.83, p = 0.008) of dependence of repeatability on the mean value (repeatability is worse for bigger mean), there is also statistically significant evidence (Spearman rho = 0.94, p = 0.001) of dependence of reproducibility on the mean value (reproducibility is worse for bigger mean). This relationship between s and m can be represented by a straight line s = a + bm. Final repeatability standard deviation = s_r = 0.022 + 0.034 m. Final reproducibility standard deviation = s_r = 0.054 + 0.117 m. Note that the precision becomes poor at concentrations below 0.5 μ/l.